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This book provides an overview of norovirus, a viral infection that adversely affects the gastrointestinal system. Unfortunately, there is no specific treatment available for this illness. As such, the World Health Organization (WHO) has identified norovirus as a priority disease for vaccine development. Chapters in this edited volume cover such topics as examination methods and genome mechanisms of norovirus, and clinical and pharmaceutical developments in managing this illness.

Virus diseases.

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Epstein-Barr virus (EBV) is a fascinating microorganism, as a "double-facetted" viral agent. After primary infection, it can persist throughout a person's lifetime in a latent form, from which it can reactivate following specific stimuli (i.e., immunodepression). Unlike other herpesviruses, EBV reactivates a countless number of times with such a high replication rate that it is unable to be controlled by conventional anti-herpesvirus drugs. Moreover, for various reasons, no vaccine is currently available in the market. This book presents a comprehensive overview of EBV, including information on its potential for oncogenic activity, its various isolates, and possible vaccine candidates.

Epstein-Barr virus diseases.

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Cervical cancer is the second most prevalent cancer among women worldwide, and infection with Human Papilloma Virus (HPV) has been identified as the causal agent for this condition. The natural history of cervical cancer is characterized by slow disease progression, rendering the condition in essence preventable and even treatable when diagnosed in early stages. Pap smear and the recently introduced prophylactic vaccines are the most prominent prevention options, but despite the availability of these primary and secondary screening tools, the global burden of disease is unfortunately still very high This book will focus on the clinical and diagnostic aspects of HPV and related disease, highlighting the latest developments in this field.

Papillomavirus diseases. --- Papillomavirus infections --- Virus diseases --- Oncology

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This book focuses on the “disease aspects” of classical swine fever (CSF). The epidemiological pattern of the reemergence of CSF from wild boars and its spread to neighboring domestic pigs provides useful information for policy makers. The recent advances in diagnostics and vaccines and how each type of vaccine should be appropriately used in various field situations provide useful information for practicing veterinarians and laboratory scientists, for example, whether the vaccine virus attenuated enough to not cross the placenta to avoid sequelae, how innocuous samples like serum should be cautiously treated to avoid risk of virus spread, how various genotypes of the CSF virus evolve and compete to survive in the field, and how the CSF virus molecularly manipulates normal cell biological processes for its own advantage to survive. Phylogenetic analyses help in tracing the origin of the CSF virus responsible for each outbreak. Overall, readers should be impressed by the capabilities of CFS in pigs. We hope that this book can be a useful reference for all colleagues, whether in CSF-free or CSF-affected parts of the world.

Classical swine fever. --- Swine --- Virus diseases.

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Annotation

Oncogenic viruses. --- Tumors --- Virus diseases. --- Epstein-Barr virus diseases. --- Kaposi's sarcoma. --- Papillomaviruses. --- Virology. --- Virology.